non-ribosomal peptide synthetase activity

Gene Ontology Term: non-ribosomal peptide synthetase activity

GO ID: GO:1904091
Aspect: Molecular Function
Description: Catalysis of a multistep reaction that produce non-ribosomal peptides. The key chain-building reaction, a C-N bond-forming reaction, involves the generation of the characteristic peptide bond by nucleophilic attack of the amino group of an amino-acyl donor unit covalently bound to a downstream peptidyl carrier protein module (amino acyl-S-PCP) on the acyl group of an upstream electrophilic acyl- or peptidyl acyl-S-PCP chain, catalyzed by a condensation (C) domain. Supplementing these core chain-elongation domains are variable numbers of auxiliary domains that are responsible for modification of the growing polypeptide chain by a small set of iterated reactions including epimerization, N-methylation, and heterocyclization.
Synonyms: Oligopeptid binding involved in non-ribosomal peptide biosynthesis, Oligopeptid binding involved in non-ribosomal peptide biosynthetic process, Oligopeptid binding involved in non-ribosomal peptide formation, Oligopeptid binding involved in non-ribosomal peptide synthesis, Oligopeptid binding involved in nonribosomal peptide anabolism, Oligopeptid binding involved in nonribosomal peptide biosynthesis, Oligopeptid binding involved in nonribosomal peptide biosynthetic process, Oligopeptid binding involved in nonribosomal peptide formation, Oligopeptid binding involved in nonribosomal peptide synthesis, Oligopeptid binding involved in nonribosomal peptide synthetase, oligopeptide binding involved in non-ribosomal peptide biosynthesis, oligopeptide binding involved in non-ribosomal peptide biosynthetic process, oligopeptide binding involved in non-ribosomal peptide formation, oligopeptide binding involved in non-ribosomal peptide synthesis, oligopeptide binding involved in nonribosomal peptide anabolism, oligopeptide binding involved in nonribosomal peptide biosynthesis, oligopeptide binding involved in nonribosomal peptide biosynthetic process, oligopeptide binding involved in nonribosomal peptide formation, oligopeptide binding involved in nonribosomal peptide synthesis, oligopeptide binding involved in nonribosomal peptide synthetase, oligopeptides binding involved in non-ribosomal peptide biosynthesis, oligopeptides binding involved in non-ribosomal peptide biosynthetic process, oligopeptides binding involved in non-ribosomal peptide formation, oligopeptides binding involved in non-ribosomal peptide synthesis, oligopeptides binding involved in nonribosomal peptide anabolism, oligopeptides binding involved in nonribosomal peptide biosynthesis, oligopeptides binding involved in nonribosomal peptide biosynthetic process, oligopeptides binding involved in nonribosomal peptide formation, oligopeptides binding involved in nonribosomal peptide synthesis, oligopeptides binding involved in nonribosomal peptide synthetase, oligopeptido binding involved in non-ribosomal peptide biosynthesis, oligopeptido binding involved in non-ribosomal peptide biosynthetic process, oligopeptido binding involved in non-ribosomal peptide formation, oligopeptido binding involved in non-ribosomal peptide synthesis, oligopeptido binding involved in nonribosomal peptide anabolism, oligopeptido binding involved in nonribosomal peptide biosynthesis, oligopeptido binding involved in nonribosomal peptide biosynthetic process, oligopeptido binding involved in nonribosomal peptide formation, oligopeptido binding involved in nonribosomal peptide synthesis, oligopeptido binding involved in nonribosomal peptide synthetase, peptidyl binding involved in nonribosomal peptide biosynthesis, peptidyl binding involved in nonribosomal peptide biosynthetic process, peptidyl carrier protein, peptidyl carrier protein activity involved in nonribosomal peptide biosynthetic process, peptidyl carrier protein activity involved in nonribosomal peptide biosynthesis, PCP, peptidyl carrier protein activity