MAP kinase activity

Gene Ontology Term: MAP kinase activity

GO ID: GO:0004707
Aspect: Molecular Function
Description: Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.
Synonyms: MAP kinase 1 activity, ATP:protein phosphotransferase (MAPKK-activated) activity, Dp38, ERK, ERK1, ERK2, extracellular signal-regulated kinase activity, LeMPK3, MAP kinase 2 activity, MAP-2 kinase activity, MAPK, MBP kinase I activity, MBP kinase II activity, mitogen activated kinase activity, mitogen-activated protein kinase activity, MP kinase activity, Mpk2, myelin basic protein kinase activity, p38, p38-2, p38delta, p42 mitogen-activated protein kinase activity, p42mapk, p44mpk, PMK-1, PMK-2, PMK-3, pp42, pp44mapk, SAPK2, STK26, SAP kinase activity, SAPK, stress-activated kinase activity, stress-activated protein kinase activity, ATP:protein phosphotransferase (MAPKK-activated) activity, mitogen-activated protein kinase activity